Pattern and Model Based Analysis of Dynamic Contrast Enhanced Prostate MRI Data
نویسندگان
چکیده
E. Eyal, B. N. Bloch, E. Furman-Haran, E. M. Genega, W. C. Dewolf, G. J. Bubley, H. Degani, N. M. Rofsky, and R. E. Lenkinski Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel, Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States, Division of Urologic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States, Division of Hematology and Medical Oncology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States
منابع مشابه
Automatic Prostate Cancer Segmentation Using Kinetic Analysis in Dynamic Contrast-Enhanced MRI
Background: Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) provides functional information on the microcirculation in tissues by analyzing the enhancement kinetics which can be used as biomarkers for prostate lesions detection and characterization.Objective: The purpose of this study is to investigate spatiotemporal patterns of tumors by extracting semi-quantitative as well as w...
متن کاملEvaluation of the accuracy of dynamic contrast enhanced MRI in the diagnosis of invasive prostate neoplasm using pathological findings
Background: Prostate cancer is the most common malignancy in men and the second leading cause of death in all countries of the world. The exact mechanism of prostate cancer is not known. On the other hand, early detection of prostate cancer can lead to a complete cure. Several clinical experiments including Digital Rectum Examination (DRE), biochemistry such as Prostate Specific Antigen (PSA), ...
متن کاملEffect of Bias in Contrast Agent Concentration Measurement on Estimated Pharmacokinetic Parameters in Brain Dynamic Contrast-Enhanced Magnetic Resonance Imaging Studies
Introduction: Pharmacokinetic (PK) modeling of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is widely applied in tumor diagnosis and treatment evaluation. Precision analysis of the estimated PK parameters is essential when they are used as a measure for therapy evaluation or treatment planning. In this study, the accuracy of PK parameters in brain DCE...
متن کاملDynamic Contrast Magnetic Resonance Imaging (DCE-MRI) and Diffusion Weighted MR Imaging (DWI) for Differentiation between Benign and Malignant Salivary Gland Tumors
Background: Salivary gland tumors form nearly 3% of head and neck tumors. Due to their large histological variety and vicinity to facial nerves, pre-operative diagnosis and differentiation of benign and malignant parotid tumors are a major challenge for radiologists. Objective: The majority of these tumors are benign; however, sometimes they tend to transform into a malignant form. Functional M...
متن کاملQuantification of blood-brain-barrier permeability dysregulation and inflammatory activity in MS lesions by dynamic-contrast enhanced MR imaging
Objective: Measurement of blood-brain permeability dysfunction in active and chronic MS lesions with T1-weighted dynamic contrast-enhanced MRI to show variation in inflammatory activity Background: blood-brain-barrier perfusion characterization impaired in MS as some studies have shown recently buta comparison between perfusion parameters in contrast-enhanced and non-enhanced lesions not have ...
متن کاملPrecision in measurements of perfusion and microvascular permeability with T1-weighted dynamic contrast-enhanced MRI.
Dynamic contrast-enhanced MRI is used to estimate microvascular parameters by tracer kinetics analysis. The time for the contrast agent to travel from the artery to the tissue of interest (bolus arrival time (BAT)) is an important parameter that must be measured in such studies because inaccurate estimates or neglect of BAT contribute to inaccuracy in model fitting. Furthermore, although the pr...
متن کامل